In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding

Daniel J Stein; Joseph D Feuerstein

doi:10.7326/J22-0084

In adults using oral anticoagulants, PPI use may be associated with lower risk for upper GI bleeding

Ann Intern Med. 2022 Nov;175(11):JC129. doi: 10.7326/J22-0084. Epub 2022 Nov 1.

Authors

Daniel J Stein¹, Joseph D Feuerstein²

Affiliations

¹ Brigham and Women's Hospital, Boston, Massachusetts, USA (D.J.S.).
² Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA (J.D.F.).

PMID: 36315943
DOI: 10.7326/J22-0084

Abstract

Kurlander JE, Barnes GD, Fisher A, et al. Association of antisecretory drugs with upper gastrointestinal bleeding in patients using oral anticoagulants: a systematic review and meta-analysis. Am J Med. 2022;135:1231-43.e8. 35679879.

Publication types

Comment

MeSH terms

Adult
Anticoagulants* / adverse effects
Gastrointestinal Hemorrhage* / chemically induced
Humans
Risk

Substances

Anticoagulants